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Regulation of the innate immune system by ubiquitin and ubiquitin-like modifiers

Detection of invading pathogens by pattern recognition receptors (PRRs) is crucial for the activation of the innate immune response. These sensors signal through intertwining signaling cascades which result in the expression of pro-inflammatory cytokines and type I interferons. Conjugation, or bindi...

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Detalles Bibliográficos
Publicado en:Cytokine Growth Factor Rev
Autores principales: Oudshoorn, Diede, Versteeg, Gijs A., Kikkert, Marjolein
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier Ltd. 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7172403/
https://ncbi.nlm.nih.gov/pubmed/22964110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cytogfr.2012.08.003
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