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Regulation of the innate immune system by ubiquitin and ubiquitin-like modifiers

Detection of invading pathogens by pattern recognition receptors (PRRs) is crucial for the activation of the innate immune response. These sensors signal through intertwining signaling cascades which result in the expression of pro-inflammatory cytokines and type I interferons. Conjugation, or bindi...

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Dettagli Bibliografici
Pubblicato in:Cytokine Growth Factor Rev
Autori principali: Oudshoorn, Diede, Versteeg, Gijs A., Kikkert, Marjolein
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier Ltd. 2012
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7172403/
https://ncbi.nlm.nih.gov/pubmed/22964110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cytogfr.2012.08.003
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