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Regulation of the innate immune system by ubiquitin and ubiquitin-like modifiers

Detection of invading pathogens by pattern recognition receptors (PRRs) is crucial for the activation of the innate immune response. These sensors signal through intertwining signaling cascades which result in the expression of pro-inflammatory cytokines and type I interferons. Conjugation, or bindi...

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Detalhes bibliográficos
Publicado no:Cytokine Growth Factor Rev
Main Authors: Oudshoorn, Diede, Versteeg, Gijs A., Kikkert, Marjolein
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Ltd. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7172403/
https://ncbi.nlm.nih.gov/pubmed/22964110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cytogfr.2012.08.003
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