The PP2A(B56) phosphatase promotes the association of Cdc20 with APC/C in mitosis

PP2A comprising B56 regulatory subunit isoforms (PP2A(B56)) is a serine/threonine phosphatase essential for mitosis. At the kinetochore, PP2A(B56) both stabilizes microtubule binding and promotes silencing of the spindle assembly checkpoint (SAC) through its association with the SAC protein BubR1. C...

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Udgivet i:J Cell Sci
Main Authors: Lee, Sun Joo, Rodriguez-Bravo, Veronica, Kim, Hyunjung, Datta, Sutirtha, Foley, Emily A.
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5450194/
https://ncbi.nlm.nih.gov/pubmed/28404789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.201608
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