Role for the PP2A/B56delta phosphatase in regulating 14-3-3 release from Cdc25 to control mitosis

DNA-responsive checkpoints prevent cell cycle progression following DNA damage or replication inhibition. The mitotic activator Cdc25 is suppressed by checkpoints through inhibitory phosphorylation at Ser287 (Xenopus numbering) and docking of 14-3-3. S287 phosphorylation is a major locus of G2/M che...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Margolis, Seth S., Perry, Jennifer A., Forester, Craig M., Nutt, Leta K., Guo, Yanxiang, Jardim, Melanie J., Thomenius, Michael J., Freel, Christopher D., Darbandi, Rashid, Ahn, Jung-Hyuck, Arroyo, Jason D., Wang, Xiao-Fan, Shenolikar, Shirish, Nairn, Angus C., Dunphy, William G., Hahn, William C., Virshup, David M., Kornbluth, Sally
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2006
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789796/
https://ncbi.nlm.nih.gov/pubmed/17110335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2006.10.035
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