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The PP2A(B56) phosphatase promotes the association of Cdc20 with APC/C in mitosis

PP2A comprising B56 regulatory subunit isoforms (PP2A(B56)) is a serine/threonine phosphatase essential for mitosis. At the kinetochore, PP2A(B56) both stabilizes microtubule binding and promotes silencing of the spindle assembly checkpoint (SAC) through its association with the SAC protein BubR1. C...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Lee, Sun Joo, Rodriguez-Bravo, Veronica, Kim, Hyunjung, Datta, Sutirtha, Foley, Emily A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5450194/
https://ncbi.nlm.nih.gov/pubmed/28404789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.201608
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