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Stabilization of RNA hairpins using non-nucleotide linkers and circularization

An RNA hairpin is an essential structural element of RNA. Hairpins play crucial roles in gene expression and intermolecular recognition but are also involved in the pathogenesis of some congenital diseases. Structural studies of the hairpin motifs are impeded by their thermodynamic instability, as t...

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Bibliographische Detailangaben
Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Kiliszek, Agnieszka, Błaszczyk, Leszek, Kierzek, Ryszard, Rypniewski, Wojciech
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5449636/
https://ncbi.nlm.nih.gov/pubmed/28334744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx122
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