Crystal structures of CGG RNA repeats with implications for fragile X-associated tremor ataxia syndrome

The CGG repeats are present in the 5′-untranslated region (5′-UTR) of the fragile X mental retardation gene FMR1 and are associated with two diseases: fragile X-associated tremor ataxia syndrome (FXTAS) and fragile X syndrome (FXS). FXTAS occurs when the number of repeats is 55–200 and FXS develops...

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Hlavní autoři: Kiliszek, Agnieszka, Kierzek, Ryszard, Krzyzosiak, Wlodzimierz J., Rypniewski, Wojciech
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2011
Témata:
Structural Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3167596/
https://ncbi.nlm.nih.gov/pubmed/21596781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr368
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