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Stabilization of RNA hairpins using non-nucleotide linkers and circularization

An RNA hairpin is an essential structural element of RNA. Hairpins play crucial roles in gene expression and intermolecular recognition but are also involved in the pathogenesis of some congenital diseases. Structural studies of the hairpin motifs are impeded by their thermodynamic instability, as t...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Kiliszek, Agnieszka, Błaszczyk, Leszek, Kierzek, Ryszard, Rypniewski, Wojciech
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5449636/
https://ncbi.nlm.nih.gov/pubmed/28334744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx122
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