The chromatin remodeling complex NoRC controls replication timing of rRNA genes

The ATP-dependent chromatin remodeling complex NoRC silences a fraction of mammalian ribosomal RNA genes (rDNA) by establishing heterochromatic structures at the rDNA promoter. Here we show that NoRC also plays a role in replication timing of rDNA. rDNA is replicated in a biphasic manner, active gen...

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Udgivet i:EMBO J
Main Authors: Li, Junwei, Santoro, Raffaella, Koberna, Karel, Grummt, Ingrid
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2004
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC544905/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15577942/
https://ncbi.nlm.nih.govhttps://doi.org/10.1038/sj.emboj.7600492
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