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The chromatin remodeling complex NoRC controls replication timing of rRNA genes
The ATP-dependent chromatin remodeling complex NoRC silences a fraction of mammalian ribosomal RNA genes (rDNA) by establishing heterochromatic structures at the rDNA promoter. Here we show that NoRC also plays a role in replication timing of rDNA. rDNA is replicated in a biphasic manner, active gen...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2005
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC544905/ https://ncbi.nlm.nih.gov/pubmed/15577942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600492 |
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