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Phase Separation and Single-Chain Compactness of Charged Disordered Proteins Are Strongly Correlated
Liquid-liquid phase separation of intrinsically disordered proteins (IDPs) is a major undergirding factor in the regulated formation of membraneless organelles in the cell. The phase behavior of an IDP is sensitive to its amino acid sequence. Here we apply a recent random-phase-approximation polymer...
Enregistré dans:
| Publié dans: | Biophys J |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Biophysical Society
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5448239/ https://ncbi.nlm.nih.gov/pubmed/28483149 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.04.021 |
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