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Hypoxia treatment reverses neurodegenerative disease in a mouse model of Leigh syndrome
The most common pediatric mitochondrial disease is Leigh syndrome, an episodic, subacute neurodegeneration that can lead to death within the first few years of life, for which there are no proven general therapies. Mice lacking the complex I subunit, Ndufs4, develop a fatal progressive encephalopath...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5448167/ https://ncbi.nlm.nih.gov/pubmed/28483998 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1621511114 |
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