Cell-free chromatin from dying cancer cells integrate into genomes of bystander healthy cells to induce DNA damage and inflammation

Bystander cells of the tumor microenvironment show evidence of DNA damage and inflammation that can lead to their oncogenic transformation. Mediator(s) of cell–cell communication that brings about these pro-oncogenic pathologies has not been identified. We show here that cell-free chromatin (cfCh) r...

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書誌詳細
出版年:Cell Death Discov
主要な著者: Mittra, Indraneel, Samant, Urmila, Sharma, Suvarna, Raghuram, Gorantla V, Saha, Tannistha, Tidke, Pritishkumar, Pancholi, Namrata, Gupta, Deepika, Prasannan, Preeti, Gaikwad, Ashwini, Gardi, Nilesh, Chaubal, Rohan, Upadhyay, Pawan, Pal, Kavita, Rane, Bhagyeshri, Shaikh, Alfina, Salunkhe, Sameer, Dutt, Shilpee, Mishra, Pradyumna K, Khare, Naveen K, Nair, Naveen K, Dutt, Amit
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2017
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5447133/
https://ncbi.nlm.nih.gov/pubmed/28580170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddiscovery.2017.15
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