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Singling Out Chromosome Gains in Tumor Evolution
In this issue of Cancer Cell, Sheltzer et al. shed new light on Theodor Boveri's century-old hypothesis by demonstrating that aneuploidy characterized by single-chromosome gains acts to suppress tumorigenesis and that aneuploidy itself is a nidus for genomic instability.
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| Izdano u: | Cancer Cell |
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| Glavni autori: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2017
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5446207/ https://ncbi.nlm.nih.gov/pubmed/28196590 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2017.01.011 |
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