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Singling Out Chromosome Gains in Tumor Evolution

In this issue of Cancer Cell, Sheltzer et al. shed new light on Theodor Boveri's century-old hypothesis by demonstrating that aneuploidy characterized by single-chromosome gains acts to suppress tumorigenesis and that aneuploidy itself is a nidus for genomic instability.

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Detalhes bibliográficos
Publicado no:Cancer Cell
Main Authors: Naylor, Ryan M., van Deursen, Jan M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5446207/
https://ncbi.nlm.nih.gov/pubmed/28196590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2017.01.011
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