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Centrosome dynamics as a source of chromosomal instability

Accurate segregation of duplicated chromosomes between two daughter cells depends on bi-polar spindle formation, a metaphase state in which sister kinetochores are attached to microtubules emanating from opposite spindle poles. To ensure bi-orientation, cells possess surveillance systems that safegu...

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Publicado en:Trends Cell Biol
Main Authors: Nam, Hyun-Ja, Naylor, Ryan, van Deursen, Jan M.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4312731/
https://ncbi.nlm.nih.gov/pubmed/25455111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2014.10.002
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