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Mutation of the androgen receptor causes oncogenic transformation of the prostate

Recent evidence demonstrates that the androgen receptor (AR) continues to influence prostate cancer growth despite medical therapies that reduce circulating androgen ligands to castrate levels and/or block ligand binding. Whereas the mutation, amplification, overexpression of AR, or cross-talk betwe...

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Détails bibliographiques
Auteurs principaux: Han, Guangzhou, Buchanan, Grant, Ittmann, Michael, Harris, Jonathan M., Yu, Xiaoqing, DeMayo, Francesco J., Tilley, Wayne, Greenberg, Norman M.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC544619/
https://ncbi.nlm.nih.gov/pubmed/15657128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408925102
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