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Conditional Expression of the Androgen Receptor Induces Oncogenic Transformation of the Mouse Prostate

The androgen signaling pathway, mediated through the androgen receptor (AR), is critical in prostate tumorigenesis. However, the precise role of AR in prostate cancer development and progression still remains largely unknown. Specifically, it is unclear whether overexpression of AR is sufficient to...

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Autori principali: Zhu, Chunfang, Luong, Richard, Zhuo, Ming, Johnson, Daniel T., McKenney, Jesse K., Cunha, Gerald R., Sun, Zijie
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190896/
https://ncbi.nlm.nih.gov/pubmed/21795710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.269894
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