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Mutation of the androgen receptor causes oncogenic transformation of the prostate

Recent evidence demonstrates that the androgen receptor (AR) continues to influence prostate cancer growth despite medical therapies that reduce circulating androgen ligands to castrate levels and/or block ligand binding. Whereas the mutation, amplification, overexpression of AR, or cross-talk betwe...

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Hlavní autoři: Han, Guangzhou, Buchanan, Grant, Ittmann, Michael, Harris, Jonathan M., Yu, Xiaoqing, DeMayo, Francesco J., Tilley, Wayne, Greenberg, Norman M.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC544619/
https://ncbi.nlm.nih.gov/pubmed/15657128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408925102
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