Anti-Aβ antibody treatment promotes the rapid recovery of amyloid-associated neuritic dystrophy in PDAPP transgenic mice

Neuritic plaques are a defining feature of Alzheimer disease (AD) pathology. These structures are composed of extracellular accumulations of amyloid-β peptide (Aβ) and other plaque-associated proteins, surrounded by large, swollen axons and dendrites (dystrophic neurites) and activated glia. Dystrop...

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Hlavní autoři: Brendza, Robert P., Bacskai, Brian J., Cirrito, John R., Simmons, Kelly A., Skoch, Jesse M., Klunk, William E., Mathis, Chester A., Bales, Kelly R., Paul, Steven M., Hyman, Bradley T., Holtzman, David M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2005
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC544607/
https://ncbi.nlm.nih.gov/pubmed/15668737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200523269
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