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Selection and characterization of alanine racemase inhibitors against Aeromonas hydrophila

BACKGROUND: Combining experimental and computational screening methods has been of keen interest in drug discovery. In the present study, we developed an efficient screening method that has been used to screen 2100 small-molecule compounds for alanine racemase Alr-2 inhibitors. RESULTS: We identifie...

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Detalhes bibliográficos
Publicado no:BMC Microbiol
Main Authors: Wang, Yaping, Yang, Chao, Xue, Wen, Zhang, Ting, Liu, Xipei, Ju, Jiansong, Zhao, Baohua, Liu, Dong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5445283/
https://ncbi.nlm.nih.gov/pubmed/28545531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12866-017-1010-x
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