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Selection and characterization of alanine racemase inhibitors against Aeromonas hydrophila

BACKGROUND: Combining experimental and computational screening methods has been of keen interest in drug discovery. In the present study, we developed an efficient screening method that has been used to screen 2100 small-molecule compounds for alanine racemase Alr-2 inhibitors. RESULTS: We identifie...

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Bibliografski detalji
Izdano u:BMC Microbiol
Glavni autori: Wang, Yaping, Yang, Chao, Xue, Wen, Zhang, Ting, Liu, Xipei, Ju, Jiansong, Zhao, Baohua, Liu, Dong
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5445283/
https://ncbi.nlm.nih.gov/pubmed/28545531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12866-017-1010-x
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