Selection and characterization of alanine racemase inhibitors against Aeromonas hydrophila

BACKGROUND: Combining experimental and computational screening methods has been of keen interest in drug discovery. In the present study, we developed an efficient screening method that has been used to screen 2100 small-molecule compounds for alanine racemase Alr-2 inhibitors. RESULTS: We identifie...

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Vydáno v:BMC Microbiol
Hlavní autoři: Wang, Yaping, Yang, Chao, Xue, Wen, Zhang, Ting, Liu, Xipei, Ju, Jiansong, Zhao, Baohua, Liu, Dong
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5445283/
https://ncbi.nlm.nih.gov/pubmed/28545531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12866-017-1010-x
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