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Selection and characterization of alanine racemase inhibitors against Aeromonas hydrophila

BACKGROUND: Combining experimental and computational screening methods has been of keen interest in drug discovery. In the present study, we developed an efficient screening method that has been used to screen 2100 small-molecule compounds for alanine racemase Alr-2 inhibitors. RESULTS: We identifie...

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Bibliografische gegevens
Gepubliceerd in:BMC Microbiol
Hoofdauteurs: Wang, Yaping, Yang, Chao, Xue, Wen, Zhang, Ting, Liu, Xipei, Ju, Jiansong, Zhao, Baohua, Liu, Dong
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5445283/
https://ncbi.nlm.nih.gov/pubmed/28545531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12866-017-1010-x
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