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Selection and characterization of alanine racemase inhibitors against Aeromonas hydrophila

BACKGROUND: Combining experimental and computational screening methods has been of keen interest in drug discovery. In the present study, we developed an efficient screening method that has been used to screen 2100 small-molecule compounds for alanine racemase Alr-2 inhibitors. RESULTS: We identifie...

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Détails bibliographiques
Publié dans:BMC Microbiol
Auteurs principaux: Wang, Yaping, Yang, Chao, Xue, Wen, Zhang, Ting, Liu, Xipei, Ju, Jiansong, Zhao, Baohua, Liu, Dong
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5445283/
https://ncbi.nlm.nih.gov/pubmed/28545531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12866-017-1010-x
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