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Cognitive reserve and TMEM106B genotype modulate brain damage in presymptomatic frontotemporal dementia: a GENFI study

Frontotemporal dementia is a heterogeneous neurodegenerative disorder with around a third of cases having autosomal dominant inheritance. There is wide variability in phenotype even within affected families, raising questions about the determinants of the progression of disease and age at onset. It...

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Vydáno v:Brain
Hlavní autoři: Premi, Enrico, Grassi, Mario, van Swieten, John, Galimberti, Daniela, Graff, Caroline, Masellis, Mario, Tartaglia, Carmela, Tagliavini, Fabrizio, Rowe, James B., Laforce Jr, Robert, Finger, Elizabeth, Frisoni, Giovanni B., de Mendonça, Alexandre, Sorbi, Sandro, Gazzina, Stefano, Cosseddu, Maura, Archetti, Silvana, Gasparotti, Roberto, Manes, Marta, Alberici, Antonella, Cardoso, Manuel J., Bocchetta, Martina, Cash, David M., Ourselin, Sebastian, Padovani, Alessandro, Rohrer, Jonathan D., Borroni, Barbara
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5445253/
https://ncbi.nlm.nih.gov/pubmed/28460069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awx103
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