Population Pharmacokinetics, Pharmacodynamics, and Exploratory Exposure–Response Analyses of Apixaban in Subjects Treated for Venous Thromboembolism

Apixaban is approved for treatment of venous thromboembolism (VTE) and prevention of recurrence. Population pharmacokinetics, pharmacokinetics–pharmacodynamics (anti‐FXa activity), and exposure–response (binary bleeding and thromboembolic endpoints) of apixaban in VTE treatment subjects were charact...

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發表在:CPT Pharmacometrics Syst Pharmacol
Main Authors: Byon, W, Sweeney, K, Frost, C, Boyd, RA
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2017
主題:
Original Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5445237/
https://ncbi.nlm.nih.gov/pubmed/28547774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12184
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