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BDL-induced biliary hyperplasia, hepatic injury and fibrosis are reduced in mast cell deficient Kit(w-sh) mice
Activated mast cells (MCs) release histamine (HA) and MCs infiltrate the liver following bile duct ligation (BDL) increasing intrahepatic bile duct mass (IBDM) and fibrosis. We evaluated the effects of BDL in MC deficient mice. Methods: WT and Kit(W-sh) mice were subjected to sham or BDL for up to 7...
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| 發表在: | Hepatology |
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| Main Authors: | , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5444972/ https://ncbi.nlm.nih.gov/pubmed/28120369 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.29079 |
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