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Prolonged exposure of cholestatic rats to complete dark inhibits biliary hyperplasia and liver fibrosis
Biliary hyperplasia and liver fibrosis are common features in cholestatic liver disease. Melatonin is synthesized by the pineal gland as well as the liver. Melatonin inhibits biliary hyperplasia of bile duct-ligated (BDL) rats. Since melatonin synthesis (by the enzyme serotonin N-acetyltransferase,...
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| Main Authors: | , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4216989/ https://ncbi.nlm.nih.gov/pubmed/25214401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00288.2014 |
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