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Melatonin inhibits hypothalamic gonadotropin-releasing hormone release and reduces biliary hyperplasia and fibrosis in cholestatic rats

Melatonin is a hormone produced by the pineal gland with increased circulating levels shown to inhibit biliary hyperplasia and fibrosis during cholestatic liver injury. Melatonin also has the capability to suppress the release of hypothalamic gonadotropin-releasing hormone (GnRH), a hormone that pro...

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Publicado en:Am J Physiol Gastrointest Liver Physiol
Autores principales: McMillin, Matthew, DeMorrow, Sharon, Glaser, Shannon, Venter, Julie, Kyritsi, Konstantina, Zhou, Tianhao, Grant, Stephanie, Giang, Thao, Greene, John F., Wu, Nan, Jefferson, Brandi, Meng, Fanyin, Alpini, Gianfranco
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5792219/
https://ncbi.nlm.nih.gov/pubmed/28751425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00421.2016
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