ロード中...
Epitope-Targeting of Tertiary Protein Structure Enables Target-Guided Synthesis of a Potent in Cell Inhibitor of Botulinum Neurotoxin
Botulinum neurotoxin (BoNT) serotype A is the most lethal known toxin and has an occluded structure which prevents direct inhibition of its active site before it enters the cytosol. We combine in situ click target-guided synthesis with synthetic epitope-targeting to exploit the tertiary structure of...
保存先:
| 出版年: | Angew Chem Int Ed Engl |
|---|---|
| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5444873/ https://ncbi.nlm.nih.gov/pubmed/25925721 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201502451 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|