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BH3-mimetics and BET-inhibitors elicit enhanced lethality in malignant glioma
Drug combination therapies remain pivotal for the treatment of heterogeneous malignancies, such as glioblastomas. Here, we show a novel lethal interaction between Bcl-xL and c-myc inhibition accomplished by bromodomain protein inhibitors. Established, patient-derived xenograft and stem cell-like gli...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5444687/ https://ncbi.nlm.nih.gov/pubmed/28418907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16365 |
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