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Downregulation of Lysyl Oxidase Protects Retinal Endothelial Cells From High Glucose–Induced Apoptosis

PURPOSE: To investigate the effect of reducing high glucose (HG)-induced lysyl oxidase (LOX) overexpression and increased activity on retinal endothelial cell apoptosis. METHODS: Rat retinal endothelial cells (RRECs) were grown in normal (N) or HG (30 mM glucose) medium for 7 days. In parallel, RREC...

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Bibliographische Detailangaben
Veröffentlicht in:Invest Ophthalmol Vis Sci
Hauptverfasser: Kim, Dongjoon, Mecham, Robert P., Trackman, Philip C., Roy, Sayon
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Association for Research in Vision and Ophthalmology 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5444550/
https://ncbi.nlm.nih.gov/pubmed/28538980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.16-21340
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