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Effects of High Glucose–Induced Lysyl Oxidase Propeptide on Retinal Endothelial Cell Survival: Implications for Diabetic Retinopathy

Diabetic retinopathy (DR) is characterized by apoptotic cell loss in the retinal vasculature. Lysyl oxidase propeptide (LOX-PP), released during LOX processing, has been implicated in promoting apoptosis in various diseased tissues. However, its role in the development and progression of DR is unkno...

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Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Kim, Dongjoon, Lee, Dayeun, Trackman, Philip C., Roy, Sayon
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6880772/
https://ncbi.nlm.nih.gov/pubmed/31537300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2019.06.004
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