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Inhibition of Diabetes-Induced Lysyl Oxidase Overexpression Prevents Retinal Vascular Lesions Associated With Diabetic Retinopathy

PURPOSE: The purpose of this study was to investigate the effect of reducing diabetes-induced lysyl oxidase (LOX) overexpression on vascular cell apoptosis and blood–retinal barrier (BRB) characteristics in diabetic rats. METHODS: Nondiabetic rats, diabetic rats, and diabetic rats intravitreally (IV...

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Veröffentlicht in:Invest Ophthalmol Vis Sci
Hauptverfasser: Song, Brian, Kim, Dongjoon, Nguyen, Ngan-Ha, Roy, Sayon
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Association for Research in Vision and Ophthalmology 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6295938/
https://ncbi.nlm.nih.gov/pubmed/30550614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.18-25543
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