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Definition of the nature and hapten threshold of the β-lactam antigen required for T cell activation in vitro and in patients
Covalent modification of protein by drugs may disrupt self-tolerance leading to lymphocyte activation. Determination of the threshold required for this process has not hitherto been possible. We have therefore performed quantitative mass spectrometric analyses to define the epitopes formed in tolera...
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| Publicat a: | J Immunol |
|---|---|
| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5444528/ https://ncbi.nlm.nih.gov/pubmed/28438900 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700209 |
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