Mass spectrometric characterization of circulating and functional antigens derived from piperacillin in patients with cystic fibrosis()

A mechanistic understanding of the relationship between the chemistry of drug antigen formation and immune function is lacking. Thus, mass spectrometric methods were employed to detect and fully characterize circulating antigens derived from piperacillin in patients undergoing therapy and the nature...

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Main Authors: Whitaker, Paul, Meng, Xiaoli, Lavergne, Sidonie N., El-Ghaiesh, Sabah, Monshi, Manal, Earnshaw, Caroline, Peckham, Daniel, Gooi, Jimmy, Conway, Steve, Pirmohamed, Munir, Jenkins, Rosalind E., Naisbitt, Dean J., Park, B. Kevin
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145118/
https://ncbi.nlm.nih.gov/pubmed/21606251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100647
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