Structural organization of the inactive X chromosome in the mouse

X-chromosome inactivation (XCI) involves major reorganization of the X chromosome as it becomes silent and heterochromatic. During female mammalian development, XCI is triggered by upregulation of the non-coding Xist RNA from one of the two X chromosomes. Xist coats the chromosome in cis and induces...

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Gepubliceerd in:Nature
Hoofdauteurs: Giorgetti, Luca, Lajoie, Bryan R., Carter, Ava C., Attia, Mikael, Zhan, Ye, Xu, Jin, Chen, Chong Jian, Kaplan, Noam, Chang, Howard Y., Heard, Edith, Dekker, Job
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5443622/
https://ncbi.nlm.nih.gov/pubmed/27437574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature18589
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