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Structural organization of the inactive X chromosome in the mouse
X-chromosome inactivation (XCI) involves major reorganization of the X chromosome as it becomes silent and heterochromatic. During female mammalian development, XCI is triggered by upregulation of the non-coding Xist RNA from one of the two X chromosomes. Xist coats the chromosome in cis and induces...
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| Pubblicato in: | Nature |
|---|---|
| Autori principali: | , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5443622/ https://ncbi.nlm.nih.gov/pubmed/27437574 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature18589 |
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