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Menopause Is a Determinant of Breast Aromatase Expression and Its Associations With BMI, Inflammation, and Systemic Markers

CONTEXT: Most estrogen-dependent breast cancers occur after menopause, despite low levels of circulating estrogens. Breast expression of the estrogen-biosynthetic enzyme, aromatase, is proposed to drive breast cancer development after menopause. However, the effects of menopause on breast aromatase...

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Bibliografiska uppgifter
I publikationen:J Clin Endocrinol Metab
Huvudupphovsmän: Brown, Kristy A., Iyengar, Neil M., Zhou, Xi Kathy, Gucalp, Ayca, Subbaramaiah, Kotha, Wang, Hanhan, Giri, Dilip D., Morrow, Monica, Falcone, Domenick J., Wendel, Nils K., Winston, Lisle A., Pollak, Michael, Dierickx, Anneloor, Hudis, Clifford A., Dannenberg, Andrew J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Endocrine Society 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5443335/
https://ncbi.nlm.nih.gov/pubmed/28323914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2016-3606
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