Menopause Is a Determinant of Breast Aromatase Expression and Its Associations With BMI, Inflammation, and Systemic Markers

CONTEXT: Most estrogen-dependent breast cancers occur after menopause, despite low levels of circulating estrogens. Breast expression of the estrogen-biosynthetic enzyme, aromatase, is proposed to drive breast cancer development after menopause. However, the effects of menopause on breast aromatase...

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Detalhes bibliográficos
Publicado no:J Clin Endocrinol Metab
Main Authors: Brown, Kristy A., Iyengar, Neil M., Zhou, Xi Kathy, Gucalp, Ayca, Subbaramaiah, Kotha, Wang, Hanhan, Giri, Dilip D., Morrow, Monica, Falcone, Domenick J., Wendel, Nils K., Winston, Lisle A., Pollak, Michael, Dierickx, Anneloor, Hudis, Clifford A., Dannenberg, Andrew J.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2017
Assuntos:
Clinical Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5443335/
https://ncbi.nlm.nih.gov/pubmed/28323914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2016-3606
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