Menopause Is a Determinant of Breast Aromatase Expression and Its Associations With BMI, Inflammation, and Systemic Markers

CONTEXT: Most estrogen-dependent breast cancers occur after menopause, despite low levels of circulating estrogens. Breast expression of the estrogen-biosynthetic enzyme, aromatase, is proposed to drive breast cancer development after menopause. However, the effects of menopause on breast aromatase...

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Publicat a:J Clin Endocrinol Metab
Autors principals: Brown, Kristy A., Iyengar, Neil M., Zhou, Xi Kathy, Gucalp, Ayca, Subbaramaiah, Kotha, Wang, Hanhan, Giri, Dilip D., Morrow, Monica, Falcone, Domenick J., Wendel, Nils K., Winston, Lisle A., Pollak, Michael, Dierickx, Anneloor, Hudis, Clifford A., Dannenberg, Andrew J.
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2017
Matèries:
Clinical Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5443335/
https://ncbi.nlm.nih.gov/pubmed/28323914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2016-3606
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