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Using Kalirin conditional knockout mice to distinguish its role in dopamine receptor mediated behaviors

BACKGROUND: Mice lacking Kalirin-7 (Kal7(KO)), a Rho GDP/GTP exchange factor, self-administer cocaine at a higher rate than wildtype mice, and show an exaggerated locomotor response to experimenter-administered cocaine. Kal7, which localizes to post-synaptic densities at glutamatergic synapses, inte...

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Bibliografiske detaljer
Udgivet i:BMC Neurosci
Main Authors: LaRese, Taylor P., Yan, Yan, Eipper, Betty A., Mains, Richard E.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5442696/
https://ncbi.nlm.nih.gov/pubmed/28535798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-017-0363-2
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