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Analysis of Kalirin-7 Knockout Mice Reveals Different Effects in Female Mice

Estradiol treatment of ovariectomized rodents is known to affect the morphology of dendritic spines and produce behavioral and cognitive effects. Kalirin-7 (Kal7), a postsynaptic density (PSD)-localized Rho-guanine nucleotide exchange factor, is important for dendritic spine formation and stability....

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Detalhes bibliográficos
Main Authors: Mazzone, Christopher M., Larese, Taylor P., Kiraly, Drew D., Eipper, Betty A., Mains, Richard E.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3502624/
https://ncbi.nlm.nih.gov/pubmed/22989522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.112.080838
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