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Divergent Chemoenzymatic Synthesis of Asymmetrical-Core-Fucosylated and Core-Unmodified N-Glycans

A divergent chemoenzymaytic approach for the preparation of core-fucosylated and core-unmodified asymmetrical N-glycans from a common advances precursor is described. An undecasaccharide was synthesized by sequential chemical glycosylations of an orthogonally protected core fucosylated hexasaccharid...

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Detalhes bibliográficos
Publicado no:Chemistry
Main Authors: Li, Tiehai, Huang, Min, Liu, Lin, Wang, Shuo, Moremen, Kelley W., Boons, Geert-Jan
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5442444/
https://ncbi.nlm.nih.gov/pubmed/27798819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201604999
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