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Chemoenzymatic Synthesis of Asymmetrical Multi-Antennary N-Glycans to Dissect Glycan-Mediated Interactions between Human Sperm and Oocytes

Complex N-glycans of glycoproteins of the zona pellucida (ZP) of human oocytes have been implicated in the binding of spermatozoa. The termini of these unusual bi-, tri-, and tetra-antennary N-glycans consist of the tetrasaccharide sialyl-Lewis(x) (SLe(x)), which was previously identified as the min...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Chemistry
Prif Awduron: Chinoy, Zoeisha S., Friscourt, Frédéric, Capicciotti, Chantelle J., Chiu, Philip, Boons, Geert-Jan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5986622/
https://ncbi.nlm.nih.gov/pubmed/29603480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201800451
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