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Streamlining the Chemoenzymatic Synthesis of Complex N-Glycans by a Stop and Go Strategy

Contemporary chemoenzymatic approaches can provide highly complex multi-antennary N-linked glycans. These procedures are, however, very demanding and typically involve as many as 100 chemical steps to prepare advanced intermediates that can be diversified by glycosyltransferases in a branch selectiv...

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Bibliografski detalji
Izdano u:Nat Chem
Glavni autori: Liu, Lin, Prudden, Anthony R., Capicciotti, Chantelle J., Bosman, Gerlof P., Yang, Jeong-Yeh, Chapla, Digantkumar G., Moremen, Kelley W., Boons, Geert-Jan
Format: Artigo
Jezik:Inglês
Izdano: 2018
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6347513/
https://ncbi.nlm.nih.gov/pubmed/30532014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41557-018-0188-3
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