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Chemoenzymatic Synthesis of Asymmetrical Multi-Antennary N-Glycans to Dissect Glycan-Mediated Interactions between Human Sperm and Oocytes

Complex N-glycans of glycoproteins of the zona pellucida (ZP) of human oocytes have been implicated in the binding of spermatozoa. The termini of these unusual bi-, tri-, and tetra-antennary N-glycans consist of the tetrasaccharide sialyl-Lewis(x) (SLe(x)), which was previously identified as the min...

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Bibliografski detalji
Izdano u:Chemistry
Glavni autori: Chinoy, Zoeisha S., Friscourt, Frédéric, Capicciotti, Chantelle J., Chiu, Philip, Boons, Geert-Jan
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5986622/
https://ncbi.nlm.nih.gov/pubmed/29603480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201800451
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