Unique Structural Features of Membrane-Bound C-Terminal Domain Motifs Modulate Complexin Inhibitory Function

Complexin is a small soluble presynaptic protein that interacts with neuronal SNARE proteins in order to regulate synaptic vesicle exocytosis. While the SNARE-binding central helix of complexin is required for both the inhibition of spontaneous fusion and the facilitation of synchronous fusion, the...

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Vydáno v:Front Mol Neurosci
Hlavní autoři: Snead, David, Lai, Alex L., Wragg, Rachel T., Parisotto, Daniel A., Ramlall, Trudy F., Dittman, Jeremy S., Freed, Jack H., Eliezer, David
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5442187/
https://ncbi.nlm.nih.gov/pubmed/28596722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00154
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