Rearrangement of Simian Virus 40 Regulatory Region Is Not Required for Induction of Progressive Multifocal Leukoencephalopathy in Immunosuppressed Rhesus Monkeys

Rearrangements of the JC virus (JCV) regulatory region (RR) are consistently found in the brains of patients with progressive multifocal leukoencephalopathy (PML), whereas the archetype RR is present in their kidneys. In addition, the C terminus of the large T antigen (T-Ag) shows greater variabilit...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Dang, Xin, Axthelm, Michael K., Letvin, Norman L., Koralnik, Igor J.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2005
Assuntos:	Pathogenesis and Immunity
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC544112/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15650162/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.79.3.1361-1366.2005
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