Detection of JC Virus-Specific Cytotoxic T Lymphocytes in Healthy Individuals

The polyomavirus JC (JCV) infects 85% of healthy individuals, and its reactivation in a limited number of immunosuppressed people causes progressive multifocal leukoencephalopathy (PML), a severe demyelinating disease of the central nervous system. We hypothesized that JCV-specific cytotoxic T lymph...

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Detalhes bibliográficos
Main Authors: Du Pasquier, R. A., Schmitz, J. E., Jean-Jacques, J., Zheng, Y., Gordon, J., Khalili, K., Letvin, N. L., Koralnik, I. J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC514969/
https://ncbi.nlm.nih.gov/pubmed/15331755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.18.10206-10210.2004
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