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Low Frequency of Cytotoxic T Lymphocytes against the Novel HLA-A*0201-Restricted JC Virus Epitope VP1(p36) in Patients with Proven or Possible Progressive Multifocal Leukoencephalopathy

JC virus (JCV)-specific cytotoxic T lymphocytes (CTL) in peripheral blood are associated with a favorable outcome in patients with progressive multifocal leukoencephalopathy (PML). However, the frequency of these cells in the peripheral blood mononuclear cells (PBMC) of PML patients is unknown. To d...

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Detalhes bibliográficos
Main Authors: Du Pasquier, Renaud A., Kuroda, Marcelo J., Schmitz, Joern E., Zheng, Yue, Martin, Kristi, Peyerl, Fred W., Lifton, Michelle, Gorgone, Darci, Autissier, Patrick, Letvin, Norman L., Koralnik, Igor J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC254255/
https://ncbi.nlm.nih.gov/pubmed/14581528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.22.11918-11926.2003
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