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Rearrangement of Simian Virus 40 Regulatory Region Is Not Required for Induction of Progressive Multifocal Leukoencephalopathy in Immunosuppressed Rhesus Monkeys

Rearrangements of the JC virus (JCV) regulatory region (RR) are consistently found in the brains of patients with progressive multifocal leukoencephalopathy (PML), whereas the archetype RR is present in their kidneys. In addition, the C terminus of the large T antigen (T-Ag) shows greater variabilit...

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Autores principales: Dang, Xin, Axthelm, Michael K., Letvin, Norman L., Koralnik, Igor J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC544112/
https://ncbi.nlm.nih.gov/pubmed/15650162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.3.1361-1366.2005
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